| D1 | 28/04/1906 | Bolton Wanderers | 1-1 | Newcastle United | White | | Unknown | Draw |
| D1 | 21/04/1906 | Preston North End | 3-0 | Bolton Wanderers | | | Unknown | Loss |
| D1 | 16/04/1906 | Bolton Wanderers | 3-2 | Liverpool | Shepherd 2, McEwan | | Unknown | Win |
| D1 | 14/04/1906 | Bolton Wanderers | 2-1 | Middlesbrough | White 2 | | Unknown | Win |
| D1 | 07/04/1906 | Bury | 2-1 | Bolton Wanderers | White | | Unknown | Loss |
| D1 | 02/04/1906 | Blackburn Rovers | 4-1 | Bolton Wanderers | White | | Unknown | Loss |
| D1 | 31/03/1906 | Bolton Wanderers | 1-3 | Manchester City | White | | 37,322 | Loss |
| D1 | 26/03/1906 | Birmingham City | 2-5 | Bolton Wanderers | White 2, Atkinson J, Stokes 2 | | Unknown | Win |
| D1 | 24/03/1906 | Nottingham Forest | 4-0 | Bolton Wanderers | | | Unknown | Loss |
| D1 | 17/03/1906 | Bolton Wanderers | 1-0 | Sheffield Wednesday | Marsh S | | Unknown | Win |
| D1 | 10/03/1906 | Derby County | 0-1 | Bolton Wanderers | McEwan | | Unknown | Win |
| D1 | 03/03/1906 | Bolton Wanderers | 3-2 | Everton | White 2, McEwan | | Unknown | Win |
| D1 | 17/02/1906 | Bolton Wanderers | 6-2 | Sunderland | Clifford, Shepherd 4, White | | Unknown | Win |
| D1 | 03/02/1906 | Bolton Wanderers | 2-0 | Notts County | Shepherd 2 | | Unknown | Win |
| D1 | 27/01/1906 | Bolton Wanderers | 3-2 | Wolverhampton Wanderers | Opponent (og), Shepherd, White | | Unknown | Win |
| D1 | 20/01/1906 | Stoke City | 1-2 | Bolton Wanderers | White, Marsh S | | Unknown | Win |
| FAC1 | 13/01/1906 | Middlesbrough | 3-0 | Bolton Wanderers | | | Unknown | Loss |
| D1 | 02/01/1906 | Bolton Wanderers | 4-1 | Aston Villa | White, Stokes, Marsh S, Shepherd | | Unknown | Win |
| D1 | 01/01/1906 | Bolton Wanderers | 6-1 | Woolwich Arsenal | White 2, Marsh S 2, Shepherd, McEwan | | Unknown | Win |
| D1 | 30/12/1905 | Sheffield United | 5-2 | Bolton Wanderers | Stokes, Shepherd | | Unknown | Loss |
| D1 | 26/12/1905 | Aston Villa | 1-1 | Bolton Wanderers | White | | Unknown | Draw |
| D1 | 25/12/1905 | Liverpool | 2-2 | Bolton Wanderers | Shepherd 2 | | Unknown | Draw |
| D1 | 23/12/1905 | Newcastle United | 2-1 | Bolton Wanderers | Stokes | | Unknown | Loss |
| D1 | 16/12/1905 | Bolton Wanderers | 1-2 | Preston North End | Shepherd | | Unknown | Loss |
| D1 | 09/12/1905 | Middlesbrough | 4-4 | Bolton Wanderers | White 2, Shepherd 2 | | Unknown | Draw |
| D1 | 02/12/1905 | Bolton Wanderers | 4-0 | Bury | McEwan, Marsh S, White 2 | | Unknown | Win |
| D1 | 25/11/1905 | Manchester City | 3-1 | Bolton Wanderers | Shepherd | | Unknown | Loss |
| D1 | 18/11/1905 | Bolton Wanderers | 6-0 | Nottingham Forest | Shepherd 4, Marsh S, White | | Unknown | Win |
| D1 | 11/11/1905 | Sheffield Wednesday | 1-2 | Bolton Wanderers | McEwan, Stokes | | Unknown | Win |
| D1 | 04/11/1905 | Bolton Wanderers | 5-0 | Derby County | Shepherd, Marsh S 3, White | | Unknown | Win |
| D1 | 28/10/1905 | Everton | 3-1 | Bolton Wanderers | White | | Unknown | Loss |
| D1 | 21/10/1905 | Bolton Wanderers | 0-1 | Birmingham City | | | Unknown | Loss |
| D1 | 14/10/1905 | Sunderland | 3-3 | Bolton Wanderers | Shepherd 2, McEwan | | Unknown | Draw |
| D1 | 07/10/1905 | Bolton Wanderers | 1-0 | Blackburn Rovers | Shepherd | | Unknown | Win |
| D1 | 30/09/1905 | Woolwich Arsenal | 0-0 | Bolton Wanderers | | | Unknown | Draw |
| D1 | 23/09/1905 | Wolverhampton Wanderers | 2-0 | Bolton Wanderers | | | Unknown | Loss |
| D1 | 16/09/1905 | Bolton Wanderers | 1-2 | Stoke City | Marsh S | | Unknown | Loss |
| D1 | 09/09/1905 | Notts County | 3-3 | Bolton Wanderers | Marsh S, Greenhalgh S, White | | Unknown | Draw |
| D1 | 02/09/1905 | Bolton Wanderers | 1-2 | Sheffield United | Wilson T | | Unknown | Loss |