| Comp | Date | Home | Score | Away | Scorers | Video | Attendance | Result |
|---|---|---|---|---|---|---|---|---|
| D1 | 23/04/1952 | Middlesbrough | 2-0 | Bolton Wanderers | 23,591 | Loss | ||
| D1 | 19/04/1952 | Manchester City | 0-3 | Bolton Wanderers | Moir, Lofthouse, Hassall | 28,388 | Win | |
| D1 | 14/04/1952 | Bolton Wanderers | 2-1 | Fulham | Lofthouse, Holden D | 29,461 | Win | |
| D1 | 12/04/1952 | Bolton Wanderers | 2-1 | Arsenal | Moir, Lofthouse | 47,940 | Win | |
| D1 | 11/04/1952 | Fulham | 1-2 | Bolton Wanderers | Wheeler, Moir | 38,304 | Win | |
| D1 | 05/04/1952 | Blackpool | 1-0 | Bolton Wanderers | 17,374 | Loss | ||
| D1 | 29/03/1952 | Bolton Wanderers | 1-1 | Liverpool | Wheeler | 17,459 | Draw | |
| D1 | 22/03/1952 | Portsmouth | 3-0 | Bolton Wanderers | 31,135 | Loss | ||
| D1 | 15/03/1952 | Bolton Wanderers | 3-0 | Chelsea | Lofthouse, Holden D, Hassall | 31,448 | Win | |
| D1 | 08/03/1952 | Huddersfield Town | 0-2 | Bolton Wanderers | Moir, Lofthouse | 24,045 | Win | |
| D1 | 01/03/1952 | Bolton Wanderers | 2-2 | Wolverhampton Wanderers | Moir, Lofthouse | 33,294 | Draw | |
| D1 | 16/02/1952 | Sunderland | 0-2 | Bolton Wanderers | Moir, Holden D | 43,397 | Win | |
| D1 | 09/02/1952 | Charlton Athletic | 1-0 | Bolton Wanderers | 23,480 | Loss | ||
| D1 | 02/02/1952 | Bolton Wanderers | 1-2 | Derby County | Holden D | 26,596 | Loss | |
| D1 | 26/01/1952 | Bolton Wanderers | 1-4 | Burnley | Hassall | 38,149 | Loss | |
| D1 | 19/01/1952 | Preston North End | 2-2 | Bolton Wanderers | Lofthouse, Langton | 38,646 | Draw | |
| FAC3 | 12/01/1952 | West Bromwich Albion | 4-0 | Bolton Wanderers | 37,900 | Loss | ||
| D1 | 05/01/1952 | Bolton Wanderers | 1-1 | Tottenham Hotspur | Langton (pen) | 46,354 | Draw | |
| D1 | 29/12/1951 | Manchester United | 1-0 | Bolton Wanderers | 55,073 | Loss | ||
| D1 | 26/12/1951 | West Bromwich Albion | 3-2 | Bolton Wanderers | Moir, Lofthouse | 37,698 | Loss | |
| D1 | 25/12/1951 | Bolton Wanderers | 3-2 | West Bromwich Albion | Moir 2 (1 pen), Lofthouse | 32,562 | Win | |
| D1 | 22/12/1951 | Bolton Wanderers | 1-1 | Stoke City | Moir | 19,235 | Draw | |
| D1 | 15/12/1951 | Aston Villa | 1-1 | Bolton Wanderers | Howe | 28,907 | Draw | |
| D1 | 08/12/1951 | Derby County | 5-2 | Bolton Wanderers | Lofthouse, Howe | 23,838 | Loss | |
| D1 | 01/12/1951 | Bolton Wanderers | 2-1 | Manchester City | Lofthouse, Howe | 43,405 | Win | |
| D1 | 24/11/1951 | Arsenal | 4-2 | Bolton Wanderers | Moir, Webster | 50,790 | Loss | |
| D1 | 17/11/1951 | Bolton Wanderers | 1-0 | Blackpool | Garrett (og) | 38,990 | Win | |
| D1 | 10/11/1951 | Liverpool | 1-1 | Bolton Wanderers | Wheeler | 49,537 | Draw | |
| D1 | 03/11/1951 | Bolton Wanderers | 0-3 | Portsmouth | 26,299 | Loss | ||
| D1 | 27/10/1951 | Chelsea | 1-3 | Bolton Wanderers | Lofthouse 2, Codd | 45,287 | Win | |
| D1 | 20/10/1951 | Bolton Wanderers | 2-1 | Huddersfield Town | Langton (pen), Codd | 33,670 | Win | |
| D1 | 13/10/1951 | Wolverhampton Wanderers | 5-1 | Bolton Wanderers | Lofthouse | 38,413 | Loss | |
| D1 | 06/10/1951 | Bolton Wanderers | 1-1 | Sunderland | Lofthouse | 43,887 | Draw | |
| D1 | 29/09/1951 | Bolton Wanderers | 2-1 | Charlton Athletic | Moir, Webster | 37,719 | Win | |
| D1 | 22/09/1951 | Burnley | 1-3 | Bolton Wanderers | Wheeler, Moir, Webster | 37,196 | Win | |
| D1 | 15/09/1951 | Bolton Wanderers | 1-1 | Preston North End | Webster | 46,523 | Draw | |
| D1 | 08/09/1951 | Tottenham Hotspur | 2-1 | Bolton Wanderers | Langton (pen) | 61,838 | Loss | |
| D1 | 03/09/1951 | Bolton Wanderers | 3-1 | Middlesbrough | Moir, Webster, Codd | 33,811 | Win | |
| D1 | 01/09/1951 | Bolton Wanderers | 1-0 | Manchester United | Lofthouse | 55,477 | Win | |
| D1 | 29/08/1951 | Newcastle United | 0-1 | Bolton Wanderers | Moir | 49,587 | Win | |
| D1 | 25/08/1951 | Stoke City | 1-2 | Bolton Wanderers | Lofthouse, Webster | 22,442 | Win | |
| D1 | 22/08/1951 | Bolton Wanderers | 0-0 | Newcastle United | 39,942 | Draw | ||
| D1 | 18/08/1951 | Bolton Wanderers | 5-2 | Aston Villa | Moir, Lofthouse, Webster 2, Langton (pen) | 30,253 | Win |