| D2 | 29/04/1978 | Bolton Wanderers | 0-0 | Fulham | | Highlights | 34,110 | Draw |
| D2 | 26/04/1978 | Blackburn Rovers | 0-1 | Bolton Wanderers | Worthington F | | 27,835 | Win |
| D2 | 22/04/1978 | Cardiff City | 1-0 | Bolton Wanderers | | | 12,566 | Loss |
| D2 | 18/04/1978 | Bolton Wanderers | 2-0 | Crystal Palace | Whatmore, Worthington F | | 23,980 | Win |
| D2 | 15/04/1978 | Bolton Wanderers | 3-0 | Bristol Rovers | Whatmore, Worthington F 2 | | 20,393 | Win |
| D2 | 08/04/1978 | Tottenham Hotspur | 1-0 | Bolton Wanderers | | | 50,097 | Loss |
| D2 | 01/04/1978 | Bolton Wanderers | 2-0 | Orient | Allardyce, Whatmore | | 17,957 | Win |
| D2 | 27/03/1978 | Notts County | 1-1 | Bolton Wanderers | Whatmore | | 15,718 | Draw |
| D2 | 25/03/1978 | Bolton Wanderers | 2-1 | Blackpool | Reid, Jones P | | 20,506 | Win |
| D2 | 21/03/1978 | Luton Town | 2-1 | Bolton Wanderers | Jones P | | 8,306 | Loss |
| D2 | 18/03/1978 | Bolton Wanderers | 0-0 | Southampton | | | 23,770 | Draw |
| D2 | 11/03/1978 | Mansfield Town | 0-1 | Bolton Wanderers | Ritson | | 12,329 | Win |
| D2 | 07/03/1978 | Bolton Wanderers | 2-0 | Sunderland | Whatmore, Morgan W | | 20,972 | Win |
| D2 | 04/03/1978 | Bolton Wanderers | 1-1 | Brighton | Reid | | 21,405 | Draw |
| FAC5 | 27/02/1978 | Middlesbrough | 2-0 | Bolton Wanderers | | | 36,662 | Loss |
| D2 | 25/02/1978 | Stoke City | 0-0 | Bolton Wanderers | | | 19,280 | Draw |
| D2 | 18/02/1978 | Oldham Athletic | 2-2 | Bolton Wanderers | Reid, Whatmore | | 20,810 | Draw |
| FAC4 | 06/02/1978 | Bolton Wanderers | 1-0 | Mansfield Town | Worthington F | | 23,830 | Win |
| D2 | 21/01/1978 | Bolton Wanderers | 1-0 | Hull City | Whatmore | | 18,256 | Win |
| D2 | 14/01/1978 | Sheffield United | 1-5 | Bolton Wanderers | Reid, Worthington F, Nicholson P, Greaves (pen), Whatmore | | 22,603 | Win |
| FAC3R | 10/01/1978 | Bolton Wanderers | 2-1 | Tottenham Hotspur | Ritson, Jones G (aet) | | 31,314 | Win |
| FAC3 | 07/01/1978 | Tottenham Hotspur | 2-2 | Bolton Wanderers | Greaves (pen), Whatmore | | 43,731 | Draw |
| D2 | 02/01/1978 | Bolton Wanderers | 1-2 | Burnley | Whatmore | | 26,334 | Loss |
| D2 | 31/12/1977 | Millwall | 1-0 | Bolton Wanderers | | | 6,720 | Loss |
| D2 | 27/12/1977 | Blackpool | 0-2 | Bolton Wanderers | Worthington F, Whatmore | | 25,789 | Win |
| D2 | 26/12/1977 | Bolton Wanderers | 2-0 | Notts County | Allardyce, Whatmore | | 22,647 | Win |
| D2 | 17/12/1977 | Charlton Athletic | 2-1 | Bolton Wanderers | Whatmore | | 12,800 | Loss |
| D2 | 10/12/1977 | Bolton Wanderers | 6-3 | Cardiff City | Jones P 2, Reid, Whatmore, Walsh M, Morgan W | | 16,090 | Win |
| D2 | 03/12/1977 | Fulham | 2-0 | Bolton Wanderers | | | 8,162 | Loss |
| LC4 | 30/11/1977 | Bolton Wanderers | 1-3 | Leeds United | Jones G | | 33,766 | Loss |
| D2 | 26/11/1977 | Bolton Wanderers | 1-0 | Tottenham Hotspur | Greaves | | 32,266 | Win |
| D2 | 19/11/1977 | Bristol Rovers | 0-1 | Bolton Wanderers | Waldron | | 7,870 | Win |
| D2 | 12/11/1977 | Bolton Wanderers | 2-1 | Charlton Athletic | Whatmore, Wood (og) | | 15,977 | Win |
| D2 | 05/11/1977 | Orient | 1-1 | Bolton Wanderers | Greaves (pen) | | 7,547 | Draw |
| D2 | 29/10/1977 | Bolton Wanderers | 2-1 | Luton Town | Morgan W, Worthington F | | 20,113 | Win |
| LC3 | 25/10/1977 | Bolton Wanderers | 3-1 | Peterborough United | Greaves, Allardyce, Whatmore (pen) | | 14,990 | Win |
| D2 | 22/10/1977 | Southampton | 2-2 | Bolton Wanderers | Worthington F, Morgan W | | 27,296 | Draw |
| D2 | 15/10/1977 | Bolton Wanderers | 2-0 | Mansfield Town | Worthington F 2 | | 18,937 | Win |
| D2 | 08/10/1977 | Brighton | 1-2 | Bolton Wanderers | Reid, Greaves (pen) | | 27,430 | Win |
| D2 | 04/10/1977 | Bolton Wanderers | 4-2 | Blackburn Rovers | Reid, Allardyce, Greaves 2 | | 18,240 | Win |
| D2 | 01/10/1977 | Bolton Wanderers | 1-1 | Stoke City | Worthington F | | 20,799 | Draw |
| D2 | 24/09/1977 | Crystal Palace | 2-1 | Bolton Wanderers | Whatmore | | 23,604 | Loss |
| D2 | 17/09/1977 | Sunderland | 0-2 | Bolton Wanderers | Whatmore, Reid | | 30,342 | Win |
| D2 | 10/09/1977 | Bolton Wanderers | 1-0 | Oldham Athletic | Whatmore | | 16,033 | Win |
| D2 | 03/09/1977 | Hull City | 0-0 | Bolton Wanderers | | | 10,106 | Draw |
| LC2 | 31/08/1977 | Bolton Wanderers | 1-0 | Lincoln City | Waldron | | 11,467 | Win |
| D2 | 27/08/1977 | Bolton Wanderers | 2-1 | Sheffield United | Reid, Whatmore | | 16,840 | Win |
| D2 | 23/08/1977 | Bolton Wanderers | 2-1 | Millwall | Allardyce, Whatmore | | 14,874 | Win |
| D2 | 20/08/1977 | Burnley | 0-1 | Bolton Wanderers | Greaves | | 14,716 | Win |