| D1 | 01/05/1926 | Bolton Wanderers | 0-2 | Everton | | | 11,883 | Loss |
| D1 | 28/04/1926 | Bolton Wanderers | 1-1 | Arsenal | Smith J | | 22,198 | Draw |
| D1 | 26/04/1926 | Aston Villa | 2-2 | Bolton Wanderers | Butler W, Vizard | | 13,093 | Draw |
| FACF | 24/04/1926 | Bolton Wanderers | 1-0 | Manchester City | Jack D (played at Wembley Stadium) | Highlights | 91,447 | Win |
| D1 | 17/04/1926 | Bolton Wanderers | 2-1 | Sheffield United | Butler W, Smith J (pen) | | 13,133 | Win |
| D1 | 12/04/1926 | Huddersfield Town | 3-0 | Bolton Wanderers | | | 20,829 | Loss |
| D1 | 10/04/1926 | Cardiff City | 0-1 | Bolton Wanderers | Jack R R | | 13,787 | Win |
| D1 | 07/04/1926 | Bolton Wanderers | 3-2 | Sunderland | Jack D 2, Jack R R | | 12,076 | Win |
| D1 | 05/04/1926 | Liverpool | 2-2 | Bolton Wanderers | Boston, Jack R R | | 21,398 | Draw |
| D1 | 03/04/1926 | Bolton Wanderers | 1-1 | Tottenham Hotspur | Vizard | | 21,364 | Draw |
| D1 | 02/04/1926 | Bolton Wanderers | 0-1 | Liverpool | | | 30,298 | Loss |
| D1 | 29/03/1926 | Manchester City | 1-1 | Bolton Wanderers | Vizard | | 21,720 | Draw |
| FACSF | 27/03/1926 | Bolton Wanderers | 3-0 | Swansea Town | Baggett, Smith J 2 (1 pen) (played at White Hart Lane, London) | Highlights | 25,476 | Win |
| D1 | 17/03/1926 | Bolton Wanderers | 3-1 | Manchester United | Roberts C 2, Baggett | | 10,794 | Win |
| FACQF2R | 15/03/1926 | Bolton Wanderers | 1-0 | Nottingham Forest | Smith J (played at Old Trafford, Manchester) | | 30,952 | Win |
| D1 | 13/03/1926 | West Bromwich Albion | 0-3 | Bolton Wanderers | Baggett 2, Jack R R | | 15,833 | Win |
| FACQFR | 10/03/1926 | Bolton Wanderers | 0-0 | Nottingham Forest | (aet) | | 29,752 | Draw |
| FACQF | 06/03/1926 | Nottingham Forest | 2-2 | Bolton Wanderers | Butler W 2 | Highlights | 26,216 | Draw |
| D1 | 27/02/1926 | Blackburn Rovers | 3-0 | Bolton Wanderers | | | 21,348 | Loss |
| FAC5 | 20/02/1926 | Bolton Wanderers | 3-0 | South Shields | Smith J (pen), Jack D, Smith J R | Highlights | 48,166 | Win |
| D1 | 13/02/1926 | West Ham United | 6-0 | Bolton Wanderers | | | 24,062 | Loss |
| D1 | 06/02/1926 | Bolton Wanderers | 2-2 | Leicester City | Smith J 2 (2 pens) | | 17,939 | Draw |
| FAC4R | 03/02/1926 | Bolton Wanderers | 6-2 | Bournemouth | Boston, Smith J 2, Jack D, Smith J R 2 | | 24,798 | Win |
| FAC4 | 30/01/1926 | Bournemouth | 2-2 | Bolton Wanderers | Smith J R, Jack D | | 12,000 | Draw |
| D1 | 23/01/1926 | Bolton Wanderers | 2-1 | Notts County | Smith J R 2 | | 15,507 | Win |
| D1 | 16/01/1926 | Bolton Wanderers | 3-2 | Bury | Baggett, Vizard, Smith J R | | 36,654 | Win |
| FAC3 | 09/01/1926 | Bolton Wanderers | 1-0 | Accrington Stanley | Jack D | | 32,875 | Win |
| D1 | 02/01/1926 | Newcastle United | 5-1 | Bolton Wanderers | Vizard | | 34,136 | Loss |
| D1 | 01/01/1926 | Bolton Wanderers | 5-3 | Birmingham City | Jack D, Vizard, Smith J R 3 | | 22,240 | Win |
| D1 | 25/12/1925 | Manchester United | 2-1 | Bolton Wanderers | Jack D | | 38,503 | Loss |
| D1 | 19/12/1925 | Everton | 2-1 | Bolton Wanderers | Butler W | | 26,400 | Loss |
| D1 | 12/12/1925 | Bolton Wanderers | 6-1 | Huddersfield Town | Butler W, Smith J 2, Jack D, Smith J R 2 | | 25,823 | Win |
| D1 | 05/12/1925 | Sheffield United | 2-0 | Bolton Wanderers | | | 20,014 | Loss |
| D1 | 28/11/1925 | Bolton Wanderers | 0-1 | Cardiff City | | | 21,520 | Loss |
| D1 | 21/11/1925 | Tottenham Hotspur | 2-3 | Bolton Wanderers | Baggett, Jack D, Vizard | | 26,792 | Win |
| D1 | 14/11/1925 | Bolton Wanderers | 5-1 | Manchester City | Jack D 2, Vizard, Smith J, Baggett | | 22,326 | Win |
| D1 | 07/11/1925 | Birmingham City | 0-1 | Bolton Wanderers | Baggett | | 22,134 | Win |
| D1 | 31/10/1925 | Bolton Wanderers | 2-2 | West Bromwich Albion | Howarth N, Jack D | | 17,063 | Draw |
| D1 | 24/10/1925 | Sunderland | 2-1 | Bolton Wanderers | Smith J (pen) | | 23,516 | Loss |
| D1 | 17/10/1925 | Bolton Wanderers | 2-2 | Blackburn Rovers | Smith J (pen), Baggett | | 19,468 | Draw |
| D1 | 10/10/1925 | Arsenal | 2-3 | Bolton Wanderers | Vizard 3 | | 41,076 | Win |
| D1 | 03/10/1925 | Bolton Wanderers | 1-0 | West Ham United | Jack D | | 20,923 | Win |
| D1 | 26/09/1925 | Leicester City | 5-2 | Bolton Wanderers | Smith J R, Jack D | | 23,820 | Loss |
| D1 | 19/09/1925 | Bolton Wanderers | 1-3 | Aston Villa | Vizard | | 16,982 | Loss |
| D1 | 16/09/1925 | Bolton Wanderers | 4-2 | Burnley | Jack D, Smith J R, Smith J 2 | | 16,647 | Win |
| D1 | 12/09/1925 | Notts County | 3-0 | Bolton Wanderers | | | 18,587 | Loss |
| D1 | 09/09/1925 | Burnley | 1-1 | Bolton Wanderers | Butler W | | 14,295 | Draw |
| D1 | 07/09/1925 | Bolton Wanderers | 1-0 | Leeds United | Smith J | | 23,343 | Win |
| D1 | 05/09/1925 | Bury | 0-5 | Bolton Wanderers | Smith J R 2, Smith J 2 (1 pen), Jack D | | 23,093 | Win |
| D1 | 31/08/1925 | Leeds United | 2-1 | Bolton Wanderers | Vizard | | 24,188 | Loss |
| D1 | 29/08/1925 | Bolton Wanderers | 2-2 | Newcastle United | Smith J, Jack D | | 30,998 | Draw |