| PL | 09/05/2010 | Bolton Wanderers | 2-1 | Birmingham City | Davies K, Klasnic | | 22,863 | Win |
| PL | 01/05/2010 | Tottenham Hotspur | 1-0 | Bolton Wanderers | | | 35,852 | Loss |
| PL | 24/04/2010 | Bolton Wanderers | 2-2 | Portsmouth | Klasnic, Davies K | | 20,526 | Draw |
| PL | 17/04/2010 | Stoke City | 1-2 | Bolton Wanderers | Taylor 2 | | 27,250 | Win |
| PL | 13/04/2010 | Chelsea | 1-0 | Bolton Wanderers | | | 40,539 | Loss |
| PL | 03/04/2010 | Bolton Wanderers | 0-1 | Aston Villa | | | 21,111 | Loss |
| PL | 27/03/2010 | Bolton Wanderers | 0-4 | Manchester United | | | 25,370 | Loss |
| PL | 20/03/2010 | Everton | 2-0 | Bolton Wanderers | | | 36,503 | Loss |
| PL | 13/03/2010 | Bolton Wanderers | 4-0 | Wigan Athletic | Elmander, Davies K (pen), Muamba, Taylor | | 20,053 | Win |
| PL | 09/03/2010 | Sunderland | 4-0 | Bolton Wanderers | | | 36,087 | Loss |
| PL | 06/03/2010 | West Ham United | 1-2 | Bolton Wanderers | Davies K, Wilshere | | 33,824 | Win |
| PL | 27/02/2010 | Bolton Wanderers | 1-0 | Wolverhampton Wanderers | Knight | | 21,261 | Win |
| FAC5R | 24/02/2010 | Tottenham Hotspur | 4-0 | Bolton Wanderers | | | 31,436 | Loss |
| PL | 21/02/2010 | Blackburn Rovers | 3-0 | Bolton Wanderers | | | 23,888 | Loss |
| PL | 17/02/2010 | Wigan Athletic | 0-0 | Bolton Wanderers | | | 18,089 | Draw |
| FAC5 | 14/02/2010 | Bolton Wanderers | 1-1 | Tottenham Hotspur | Davies K | | 13,596 | Draw |
| PL | 09/02/2010 | Manchester City | 2-0 | Bolton Wanderers | | | 42,016 | Loss |
| PL | 06/02/2010 | Bolton Wanderers | 0-0 | Fulham | | | 22,289 | Draw |
| PL | 30/01/2010 | Liverpool | 2-0 | Bolton Wanderers | | | 43,413 | Loss |
| PL | 26/01/2010 | Bolton Wanderers | 1-0 | Burnley | Chung-Yong | | 23,986 | Win |
| FAC4 | 23/01/2010 | Bolton Wanderers | 2-0 | Sheffield United | Steinsson, Elmander | | 14,572 | Win |
| PL | 20/01/2010 | Arsenal | 4-2 | Bolton Wanderers | Cahill, Taylor (pen) | | 59,084 | Loss |
| PL | 17/01/2010 | Bolton Wanderers | 0-2 | Arsenal | | | 23,893 | Loss |
| FAC3 | 02/01/2010 | Bolton Wanderers | 4-0 | Lincoln City | Swaibu (og), Chung-Yong, Cahill, Davies M | | 11,193 | Win |
| PL | 29/12/2009 | Bolton Wanderers | 2-2 | Hull City | Klasnic, Davies K | | 20,696 | Draw |
| PL | 26/12/2009 | Burnley | 1-1 | Bolton Wanderers | Taylor | | 21,761 | Draw |
| PL | 15/12/2009 | Bolton Wanderers | 3-1 | West Ham United | Chung-Yong, Klasnic, Cahill | | 17,849 | Win |
| PL | 12/12/2009 | Bolton Wanderers | 3-3 | Manchester City | Klasnic 2, Cahill | | 22,735 | Draw |
| PL | 05/12/2009 | Wolverhampton Wanderers | 2-1 | Bolton Wanderers | Elmander | | 27,362 | Loss |
| PL | 28/11/2009 | Fulham | 1-1 | Bolton Wanderers | Klasnic | | 23,554 | Draw |
| PL | 22/11/2009 | Bolton Wanderers | 0-2 | Blackburn Rovers | | | 21,777 | Loss |
| PL | 07/11/2009 | Aston Villa | 5-1 | Bolton Wanderers | Elmander | | 38,101 | Loss |
| PL | 31/10/2009 | Bolton Wanderers | 0-4 | Chelsea | | | 22,680 | Loss |
| LC4 | 28/10/2009 | Chelsea | 4-0 | Bolton Wanderers | | | 41,538 | Loss |
| PL | 25/10/2009 | Bolton Wanderers | 3-2 | Everton | Chung-Yong, Cahill, Klasnic | | 21,547 | Win |
| PL | 17/10/2009 | Manchester United | 2-1 | Bolton Wanderers | Taylor | | 75,103 | Loss |
| PL | 03/10/2009 | Bolton Wanderers | 2-2 | Tottenham Hotspur | Gardner, Davies K | | 21,305 | Draw |
| PL | 26/09/2009 | Birmingham City | 1-2 | Bolton Wanderers | Cohen, Chung-Yong | | 28,671 | Win |
| LC3 | 22/09/2009 | Bolton Wanderers | 3-1 | West Ham United | Davies K, Cahill, Elmander (aet) | | 8,050 | Win |
| PL | 19/09/2009 | Bolton Wanderers | 1-1 | Stoke City | Taylor (pen) | | 20,265 | Draw |
| PL | 12/09/2009 | Portsmouth | 2-3 | Bolton Wanderers | Cohen, Taylor (pen), Cahill | | 17,564 | Win |
| PL | 29/08/2009 | Bolton Wanderers | 2-3 | Liverpool | Davies K, Cohen | | 23,284 | Loss |
| LC2 | 25/08/2009 | Tranmere Rovers | 0-1 | Bolton Wanderers | Davies M | Highlights | 5,381 | Win |
| PL | 22/08/2009 | Hull City | 1-0 | Bolton Wanderers | | | 22,999 | Loss |
| PL | 15/08/2009 | Bolton Wanderers | 0-1 | Sunderland | | | 22,247 | Loss |