| D1 | 24/04/1954 | Huddersfield Town | 2-1 | Bolton Wanderers | Parry R | | 25,635 | Loss |
| D1 | 19/04/1954 | Burnley | 1-1 | Bolton Wanderers | Parry R | | 25,857 | Draw |
| D1 | 17/04/1954 | Bolton Wanderers | 3-2 | Blackpool | Moir, Hassall, Lofthouse | | 40,291 | Win |
| D1 | 16/04/1954 | Bolton Wanderers | 0-0 | Burnley | | | 34,394 | Draw |
| D1 | 10/04/1954 | Chelsea | 2-0 | Bolton Wanderers | | | 49,433 | Loss |
| D1 | 03/04/1954 | Bolton Wanderers | 3-1 | Arsenal | Moir, Hassall (pen), Lofthouse | | 30,525 | Win |
| D1 | 27/03/1954 | Portsmouth | 3-2 | Bolton Wanderers | Moir, Parry R | | 22,784 | Loss |
| D1 | 24/03/1954 | Wolverhampton Wanderers | 1-1 | Bolton Wanderers | Lofthouse | | 19,617 | Draw |
| D1 | 20/03/1954 | Bolton Wanderers | 3-0 | Aston Villa | Hassall 2, Stevens D | | 26,292 | Win |
| FACQFR | 17/03/1954 | Bolton Wanderers | 0-2 | Sheffield Wednesday | | | 52,568 | Loss |
| FACQF | 13/03/1954 | Sheffield Wednesday | 1-1 | Bolton Wanderers | Moir (pen) | | 65,000 | Draw |
| D1 | 06/03/1954 | Bolton Wanderers | 3-1 | Sunderland | Moir, Parry R, Stevens D | | 26,379 | Win |
| D1 | 03/03/1954 | Tottenham Hotspur | 3-2 | Bolton Wanderers | Moir, Lofthouse | | 16,720 | Loss |
| D1 | 27/02/1954 | Manchester City | 3-0 | Bolton Wanderers | | | 39,340 | Loss |
| FAC5R | 24/02/1954 | Portsmouth | 1-2 | Bolton Wanderers | Moir (2) | Highlights | 45,806 | Win |
| FAC5 | 20/02/1954 | Bolton Wanderers | 0-0 | Portsmouth | | | 53,883 | Draw |
| D1 | 13/02/1954 | Bolton Wanderers | 0-2 | Preston North End | | | 44,639 | Loss |
| D1 | 06/02/1954 | Bolton Wanderers | 3-0 | Cardiff City | Moir, Stevens D, Lofthouse | | 30,777 | Win |
| FAC4 | 30/01/1954 | Headington United | 2-4 | Bolton Wanderers | Moir, Parry R, Lofthouse, Stevens D | Highlights | 16,600 | Win |
| D1 | 23/01/1954 | Manchester United | 1-5 | Bolton Wanderers | Moir, Parry R 2, Lofthouse 2 | | 48,505 | Win |
| D1 | 16/01/1954 | Bolton Wanderers | 2-2 | Newcastle United | Moir, Lofthouse | | 29,476 | Draw |
| FAC3 | 09/01/1954 | Bolton Wanderers | 1-0 | Liverpool | Moir | | 45,340 | Win |
| D1 | 02/01/1954 | Liverpool | 1-2 | Bolton Wanderers | Moir, Stevens D | | 44,383 | Win |
| D1 | 01/01/1954 | Bolton Wanderers | 2-1 | Sheffield United | Lofthouse, Coldwell (og) | | 37,484 | Win |
| D1 | 26/12/1953 | Bolton Wanderers | 3-1 | Charlton Athletic | Wheeler, Moir, Lofthouse | | 36,065 | Win |
| D1 | 25/12/1953 | Charlton Athletic | 1-0 | Bolton Wanderers | | | 19,226 | Loss |
| D1 | 19/12/1953 | Bolton Wanderers | 2-1 | West Bromwich Albion | Wheeler, Lofthouse | | 32,246 | Win |
| D1 | 12/12/1953 | Sheffield United | 3-0 | Bolton Wanderers | | | 27,769 | Loss |
| D1 | 05/12/1953 | Bolton Wanderers | 0-0 | Huddersfield Town | | | 36,077 | Draw |
| D1 | 28/11/1953 | Blackpool | 0-0 | Bolton Wanderers | | | 29,464 | Draw |
| D1 | 21/11/1953 | Bolton Wanderers | 2-2 | Chelsea | Wheeler, Lofthouse | | 30,635 | Draw |
| D1 | 14/11/1953 | Arsenal | 4-3 | Bolton Wanderers | Moir, Hassall (pen), Wheeler | | 52,319 | Loss |
| D1 | 07/11/1953 | Bolton Wanderers | 6-1 | Portsmouth | Holden D, Lofthouse (2), Hassall (3) (1 pen) | | 22,441 | Win |
| D1 | 31/10/1953 | Aston Villa | 2-2 | Bolton Wanderers | Moir, Lofthouse | | 25,325 | Draw |
| D1 | 24/10/1953 | Bolton Wanderers | 1-1 | Wolverhampton Wanderers | Moir | | 40,027 | Draw |
| D1 | 17/10/1953 | Sunderland | 1-2 | Bolton Wanderers | Wheeler, Lofthouse | | 45,358 | Win |
| D1 | 10/10/1953 | Bolton Wanderers | 3-2 | Manchester City | Moir, Allcock 2 | | 34,443 | Win |
| D1 | 03/10/1953 | Bolton Wanderers | 2-0 | Tottenham Hotspur | Hassall, Lofthouse | | 39,842 | Win |
| D1 | 26/09/1953 | Preston North End | 3-1 | Bolton Wanderers | Moir | | 39,553 | Loss |
| D1 | 19/09/1953 | Cardiff City | 1-1 | Bolton Wanderers | Hassall | | 35,788 | Draw |
| D1 | 16/09/1953 | Sheffield Wednesday | 2-1 | Bolton Wanderers | Hassall | | 26,025 | Loss |
| D1 | 12/09/1953 | Bolton Wanderers | 0-0 | Manchester United | | | 48,591 | Draw |
| D1 | 09/09/1953 | Bolton Wanderers | 2-1 | Sheffield Wednesday | Moir, Hassall (pen) | | 31,143 | Win |
| D1 | 05/09/1953 | Newcastle United | 2-3 | Bolton Wanderers | Hassall (pen), Webster 2 | | 61,321 | Win |
| D1 | 02/09/1953 | Middlesbrough | 3-2 | Bolton Wanderers | Wheeler, Hassall | | 25,458 | Loss |
| D1 | 29/08/1953 | Bolton Wanderers | 2-0 | Liverpool | Moir, Webster | | 27,258 | Win |
| D1 | 26/08/1953 | Bolton Wanderers | 3-2 | Middlesbrough | Hassall 2 (1 pen), Webster | | 29,502 | Win |
| D1 | 22/08/1953 | West Bromwich Albion | 1-1 | Bolton Wanderers | Moir | | 28,975 | Draw |